|
Differential diagnosis
of Fe
Deficiency Anaemia
|
| Ferritin and ESR are combined in a
discriminant function which gives the probability of the patient
having iron deficiency anaemia (FDA). The ESR compensates for the
effect of other disease processes such as inflammation, liver disease
and malignancy. |
| Ferritin |
|
| ESR |
|
| FDA |
|
|
| Probability: |
|
| Formula: |
P = 1 / (1 + exp(1.311*Ferritin - 0.6213*ESR - 12.17)) |
| Reference: |
Witte J et al. AJCP 1986; 85: 202 - 206. Other workers
are not convinced and you are recommended to read:- Coenen et al.
Clinical Chemistry 1991; 4: 560 - 563 and the Editorial by Witte in
the same issue. |