return to haematology guidance

 

MANAGEMENT OF ANTICOAGULATED PATIENTS THROUGH SURGERY

Category Management
Low risk patients ie on warfarin for: atrial fibrillation, DVT, PE, Recurrent VT, Arterial Disease 1) Stop warfarin 3 days pre-op
2) Aim for INR <2.5 immediately pre-op
3) If INR <1.5 immediately pre-op consider usual thromboprophylaxis for type of operation proposed.
4)Restart oral anticoagulation at normal maintenance dose on the evening following the operation when the patient is able to tolerate oral medication.
Intermediate Risk Patients ie Patients with mechanical heart valve replacements Minor ops – i.e. when the patient can be expected to resume warfarin within 24 hours post-op - as above
Major ops – when they will be expected to be unable to take oral warfarin for more than 24 hours - as below
Patients with life threatening thrombosis 1) Aim to admit the patient one day pre-op with INR of approx. 2.5 (for a stable anticoagulant patient with a mitral mechanical valve replacement (INR therapeutic range 3.0-4.0), advise patient to stop warfarin 3 days pre-op)


2) 
Check INR/APTT daily from admission and when the INR is <3.0 start IV heparin infusion (20,000-40,000 IV/day).

3) Maintain heparinisation pre and post-operatively

4) Convert to warfarin post-op once patient is stable

 

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