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Synonyms |
|
CSF
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Clinical
Indications |
|
Demonstration
of the presence of oligoclonal bands in the CSF is used
in the diagnosis of multiple sclerosis (MS) and other
related conditions.
|
|
Request
Form |
|
Combined
Pathology Blood form (Yellow/Black)
|
|
Availability |
|
On
request.
|
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Specific
Criteria |
|
The
following must be indicated on the request form:
- Clinical indication for request - provisional or
differential diagnosis.
- Length of history
- Myelogram etc. as available.
|
|
Turnaround
Time |
|
2
weeks
|
|
Specimen |
|
For
optimum analysis and interpretation it is important that
the CSF samples is accompanied by a serum sample taken
the same day.
|
|
Volume |
|
Minimum
of 0.5 ml.
|
|
Container |
|
White Capped
Universal. Ensure a serum sample (Yellow top SST) has
also been taken same day.
|
|
Lab.
Handling |
|
Store
at 4C. (OLIG & send; NOOLI &
save)
|
|
Causes for
Rejection |
|
Insufficient clinical information.
|
|
Interpretation |
|
Oligoclonal
bands will be found in over 90% of patients with
clinically definitive MS, but may also be found in other
inflammatory lesions affecting the CNS. Presence of
identical oligoclonal bands in both CSF and serum
suggests a systemic process such as Guillain-Barre
syndrome.
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|
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