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Test Directory - Gonadotrophins

Synonyms

Luteinising Hormone (LH) and Follicle Stimulating Hormone (FSH)

Clinical Indications

LH and FSH are anterior pituitary hormones which regulate male and female gonadal function. Measurement of LH/FSH can be useful in suspected disorders of gonadal function.
Guidelines are available for hormone measurements in women with secondary amenorrhoea and/or menopausal symptoms.

Test Includes

LH / FSH 

Request Form

Combined Pathology Blood form (Yellow/Black)

Availability

On request

Specific Criteria

Investigation of suspected hypothalamic, pituitary or gonadal dysfunction.

Turnaround Time

Same Day (Monday to Friday)

Specimen

Serum

Volume

1 ml

Container

Yellow top (SST) tube

Collection

No specific collection conditions

Causes for Rejection

Unlabelled sample

Reference Range

In women, dependent on stage of menstral cycle; in the early follicular phase, and in men, levels of LH and FSH are usually < 10 U/L.

Interpretation

Low LH/FSH: pituitary / hypothalamic disease.
High gonadotrophins: primary gonadal failure (LH and FSH), azoospermia / ovulatory failure (FSH), polycystic ovary syndrome (LH>FSH).
Towards the menopause, FSH tends to rise before LH, although both show considerable variation. After the menopause, levels of both FSH and LH are greatly elevated (greater than 28 U/L).

        

 


Last edited 07/08/08