Synonyms |
|
Thalassaemia screen, Sickle
screen
|
Clinical Indications |
|
To confirm or exclude
presence of variant haemoglobins and or beta thalassaemia
|
Test
Includes |
|
HPLC,
HbH, Sickle screen, FBC
|
Request
Form |
|
Combined
Pathology Blood form (Yellow/Black or Blue for GP's)
|
Availability |
|
On
request
|
Specific Criteria |
|
Ethnic origin required. Family
origin questionnaire (FOQ) required if pregnant.
|
Turnaround Time |
|
|
Specimen |
|
Whole
blood (EDTA)
|
Volume |
|
3 mL.
|
Container |
|
Purple
top (EDTA) tube.
|
Lab. Handling |
|
Hb variants requiring
confirmation sent to Royal London Hospital. Variants requiring
definitive diagnosis sent to Kings College Hospital. Contact
lab first if DNA/ globin synthesis is required.
|
Causes for
Rejection |
|
Unlabelled sample.
Previously reported Haemoglobinopathy screen. Underfilled or
clotted samples
|
Reference Range |
|
Hb
F <2.0 adult , <4.0 child
Hb A2 0.9-3.1
|