Synonyms

TRAb

Clinical Indications

Positive TSH receptor antibody (TRAb) identifies the probable cause of Graves' disease. The finding of persistently positive TRAb is useful in indicating that apparent remission of Graves' disease is unlikely to be sustained. TRAb measurement may also be helpful in classification of neonatal thyroid disease and aetiology of atypical eye disease. 

Request Form 

Combined Pathology Blood form (Yellow/Black or Blue for GP's)

Availability

Analysed by referral laboratory if specific criteria met.

Specific Criteria

Requested by Consultant Endocrinologist or agreed with Consultant Biochemist. Normally, TRAb will only be undertaken if Thyroid antibodies are not positive (i.e. negative or weak positive)..

Turnaround Time

3 weeks

Specimen

Serum

Volume

0.5 ml

Container

Yellow top (SST) tube

Lab. Handling

Aliquot and store at 4C. (TRAB & send; NOTRB & save)

Causes for Rejection

Unlabelled sample

Reference Range