Clinical
Indications |
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Transferrin
saturation is used as a screening test for haemochromatosis, a
common (1 in 200-300 individuals), autosomal recessive
disorder of iron absorption, with progressively increasing
iron stores and organ damage. Not all patients with the
genetic abnormality may be symptomatic, but they remain at
risk.
Raised levels should be confirmed by genotyping for HFE
mutations.
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