Clinical
Indications |
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Low caeruloplasmin is found in
most cases of Wilson's disease. Copper accumulation produces clinical features (hepatic
disease, neurological signs, Kayser-Fleischer rings) usually in late childhood / early
adulthood. Decreased levels also found in severe liver disease.
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Request Form |
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Combined Pathology Blood form
(Yellow/Black)
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Availability |
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Analysed by
referral laboratory
if specific criteria met.
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Specific
Criteria |
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Investigation of suspected
Wilson's disease or if specifically requested by a Consultant. Investigation will normally
only be undertaken if patient less than 40 years of age.
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Turnaround
Time |
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2 weeks
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Specimen |
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Serum
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Volume |
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2 ml
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Container |
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Yellow top (SST) tube
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Lab. Handling |
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Aliquot and store at 4C. Samples should be posted
same day as collection. (CAER & send; NOCAE & save)
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Causes for
Rejection |
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Not meeting specific criteria for
analysis.
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Reference
Range |
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Adult 0.2 - 0.6 g/L; <4 months
0.08 - 0.23; up to 1 year 0.12 - 0.35; 1 to 10 years 0.20 - 0.40; 10-13 years 0.15 - 0.23.
Information
on age-related ranges
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